A "Tempest" over t-Tests

Cross-Over Analysis Using T-Tests

Cross-over designs are popular in the assessment of equivalence. In this case, the effectiveness of a new treatment formulation (drug) is to be compared against the effectiveness of the currently used (reference) formulation. When showing equivalence, it is not necessary to show that the new treatment is better than the current treatment. Rather, the new treatment need only be shown to be as go...

A Scientific Tempest

Tap water tempest

You know the news isn’t going to be good when the report of a new study cites sources in City Hall rather than the scientific literature. That’s exactly how the story broke in February, reporting a link between tap water and miscarriages in a California study. On February 10, the Los Angeles Times warned its readers in a front page report that “drinking five or more glasses of cold tap water pe...

Tempest: A Substrate for Portable Parallel Programs

This paper describes Tempest, a collection of mechanisms for communication and synchronization in parallel programs. With these mechanisms, authors of compilers, libraries, and application programs can exploit—across a wide range of hardware platforms—the best of shared memory, message passing, and hybrid combinations of the two. Because Tempest provides mechanisms, not policies, programmers ca...

New superbug or tempest in a teapot?

In mid-February this year, New York City Health Commissioner Thomas Frieden called a press conference to announce that a case of rapidly progressing, multidrugresistant HIV/AIDS had been identified. Although drug resistance is common, and rapid progression to AIDS is rare but not unheard of, it is the combination of both factors in one patient that raised the fear among public health officials ...